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atrial septal defect
- a congenital defect in the septum between the atria of the heart, caused by failure of the foramen primum or secundum to close normally; may involve endocardial cushions of the atrioventricular canal; occasionally there is strong evidence of autosomal dominant inheritance [MIM*108800]. In varying degree, it is also a common feature of the autosomal recessive Ellis-van Creveld syndrome [MIM*225500] and the autosomal dominant Holt-Oram syndrome [MIM*142900].
WebMD Medical Reference from "Stedman's Medical Dictionary"
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Stedman’s Medical Dictionary 28th Edition, Copyright© 2006_Lippincott Williams & Wilkins. All rights reserved.
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