This article is from the WebMD Feature Archive
Going Long: Secrets of Male Longevity
Give it up, Ponce de León — there are no magical fountains of youth out there, no miraculous ways to achieve a longer life. But while medical experts caution against hormone supplements, vitamin overdoses, anti-aging pills, extreme diets, and other dubious life extension tricks, there are some sound ways for men to increase their chances for a long and healthy life. Much of the advice is obvious: Don’t smoke, eat wisely, drink moderately, exercise regularly, and get annual medical check-ups. But some of the tips from geriatric specialists and male health experts are not only surprising, they sound fun.
The good news about male longevity is that much of it is under our control. Robert Butler, MD, is professor of geriatrics at the Mount Sinai School of Medicine in New York and head of the non-profit International Longevity Center. Butler says “Only about 25% of what determines the length of life we have is based on genes. The rest is up to us.” Butler says this is based on the famous Danish Twins Registry study, which began in 1954 and has yielded a huge volume of information about genetic and lifestyle factors involved in health and aging.
Long life outlook: Can a little wine (or beer) help you improve with age?
You don’t have to lead an ascetic’s existence to extend your life. In fact, recent studies show that light to moderate drinking can reduce your risk of cardiovascular death. “The key word here is moderate,” cautions Butler. “We’re probably talking about two drinks a day for men. And my own advice to folks is about one drink a day. The older you get, the heavier the impact of the alcohol. But in moderation, alcohol not only has a relaxing effect, it can elevate levels of good cholesterol.”
According to a Netherlands study released in March, wine is more beneficial than other kinds of alcohol. The life expectancy of men who drank wine was more than two years longer than those who imbibed other alcoholic beverages. Earlier studies have shown that red wine may have an additional heath benefit because the polyphenolic compounds found in the darker beverage counter the build-up of fatty tissue in the arteries that can lead to strokes or heart attacks.
The health advantages of wine over other spirits might be exaggerated, Lawrence Greenblatt, MD, believes. But Greenblatt toasts the general idea of moderate drinking. “I think the business about red wine vs. beer or some other alcohol is probably not true after you adjust for other risk factors,” says Greenblatt, an associate clinical professor of medicine at Duke University Medical Center who sees mostly male patients in his Duke Outpatient Center practice. “People who drink beer, for instance, tend to be of a lower socioeconomic status than someone drinking Cabernet at dinner. So they have other risk factors working against their life expectancy. Once you adjust for those factors, probably any kind of alcohol would be protective, in moderation.”
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.

