Men who are older than 50 have a higher risk of developing benign prostatic hyperplasia (BPH).

The hormone testosterone, which is produced mainly by the testicles, is necessary for BPH to develop. Men who have their testicles removed before puberty never develop BPH. Men who have their testicles removed after puberty (but before they have symptoms of BPH) rarely develop BPH.

A family history of BPH may increase your risk for requiring treatment for this condition, especially if a relative required treatment before age 60.

A vasectomy does not increase your risk of BPH.