Klinefelter Syndrome - Symptoms
There generally are no obvious signs of Klinefelter syndrome until puberty. At this time, boys with Klinefelter syndrome often do not have the increase in testosterone levels that normally occurs.
Because of low testosterone levels, boys with Klinefelter syndrome may:
- Have sparse pubic, facial, and body hair.
- Have underdeveloped muscles.
- Have enlarged
breasts (gynecomastia
). - Be taller than other males in their family and have long legs, narrow shoulders, and wide hips.
Most men with Klinefelter syndrome have smaller-than-expected testicles. And many men are infertile and cannot father children without using special fertility techniques.
See a picture of a
male with Klinefelter syndrome
.
Mental, emotional, and behavioral concerns
Males with Klinefelter syndrome appear to have reduced abilities in specific areas, including:1
- Language development. Boys with Klinefelter syndrome often have delayed or slowly developing speech skills and poor verbal skills.
- Critical thinking skills, problem solving, and ability to plan.
- Multi-tasking.
- Impulse control.
- Response time.
Some research shows that these problems with learning and behavior may be caused by the way the brain grows in males who have Klinefelter syndrome.2
Boys may have emotional problems that range from being shy and immature to being overly anxious or aggressive. They may also have poor social skills, which may cause problems for them in school and in other social situations. They are at risk for developing psychiatric disorders, such as anxiety, depression, and drug and alcohol abuse.
WebMD Medical Reference from Healthwise
Klinefelter Syndrome Topics
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.

